Overview
Riverside sits at the geographic and economic center of California’s Inland Empire, a region of more than 4.6 million residents that has seen significant investment in healthcare infrastructure over the past decade. Riverside Community Hospital, Loma Linda University Health, and a growing network of specialty practices have collectively expanded access to advanced treatments — including regenerative and orthobiologic medicine — that were once only available in Los Angeles or San Diego. Patients in the 92501, 92503, 92506, and surrounding ZIP codes now have access to fellowship-trained physicians offering interventional pain management and biological therapies without the need to travel to the coast.
Regenerative medicine broadly refers to a category of treatments designed to support or accelerate the body’s own tissue repair mechanisms. The two most clinically established modalities in an outpatient orthopedic and pain management context are platelet-rich plasma (PRP) therapy and stem cell therapy. PRP involves drawing a patient’s own blood, centrifuging it to concentrate the platelets and growth factors, and injecting the resulting preparation into an injured or degenerative tissue site. Stem cell procedures vary more widely: some practices harvest cells from the patient’s own bone marrow or adipose (fat) tissue, while others use allogeneic sources such as umbilical cord-derived Wharton’s Jelly. Patients in Riverside typically seek these treatments for chronic joint pain, ligament and tendon injuries, spinal degeneration, and conditions where surgery has been recommended but the patient prefers to first exhaust non-surgical options.
Clinic types in Riverside range from multi-location pain management groups with board-certified PM&R (Physical Medicine and Rehabilitation) physicians, to orthopedic surgery practices that offer PRP as one component of a broader surgical and non-surgical toolkit. Not all clinics offering regenerative therapies are equivalent. The FDA classifies most stem cell therapies as investigational, meaning they are not FDA-approved treatments for specific diseases. A reputable clinic will be transparent about this regulatory status, will have named, credentialed physicians (not just medical directors listed on a corporate website), and will conduct thorough patient evaluation before recommending any biologic intervention. Avoid any clinic that guarantees outcomes, refuses to discuss risks, or declines to name its treating physicians.
Evaluating a clinic in Riverside requires looking at several factors: the treating physician’s board certification, fellowship training, and California medical license status (verifiable at mbc.ca.gov); whether the clinic performs imaging-guided injections (ultrasound or fluoroscopic guidance improves accuracy and is a marker of clinical rigor); the source and processing method of the biologic material being injected; and whether the clinic integrates regenerative treatment with a broader care plan that may include physical therapy, activity modification, and follow-up assessment. This guide covers three providers with verified Riverside-area addresses and named, credentialed physicians as of the date of publication.
Top Stem Cell Therapy Clinics in Riverside
1. Integrative Sports and Spine — Riverside
Address: 3975 Jackson Street, Suite 201, Riverside, CA 92503
Phone: (833) 476-7377
Website: https://www.integrativesportsandspine.com
Hours: Monday through Friday, 9:00 AM — 5:00 PM
About: Integrative Sports and Spine (ISS) is a multi-location Southern California practice with a Riverside clinic serving patients throughout the Inland Empire. The practice was built around Physical Medicine and Rehabilitation (PM&R) and interventional pain management, with a clinical philosophy oriented toward non-surgical treatment and functional restoration. The Riverside location at 3975 Jackson Street occupies a suite in the 92503 corridor and is staffed by physicians who rotate across the ISS network, which includes locations in Long Beach, Alhambra, and City of Industry. ISS offers multilingual services in English, Spanish, Korean, and Vietnamese — a practical advantage in Riverside County’s diverse patient population. The practice accepts Medicare, PPO insurance plans, and self-pay, and uses ultrasound guidance and certified laboratory processing for regenerative procedures.
Physicians:
- Henry K. Lee, DO — CEO and Medical Director, Interventional Pain and PM&R. Dr. Lee earned his medical degree from Kansas City University of Medicine and Biosciences (2009), completed his residency in Physical Medicine and Rehabilitation at Jackson Memorial Hospital / University of Miami, and completed an Interventional Pain Medicine fellowship at Virginia Commonwealth University. He is board certified in both Physical Medicine and Rehabilitation (ABPMR) and Pain Medicine. Dr. Lee is a member of the American Academy of Physical Medicine and Rehabilitation (AAPM&R), the American Society of Interventional Pain Physicians (ASIPP), and the American Medical Association (AMA). He brings over 16 years of clinical experience in musculoskeletal and sports medicine.
- Victoria S. Chang, MD — Chief Medical Officer, Interventional Pain and PM&R. Dr. Chang earned her medical degree from St. George’s University (2007) and completed her PM&R residency at Albany Medical Center in New York, followed by a pain management fellowship at Non-surgical Orthopaedics, P.C. in Georgia. She is board certified in Physical Medicine and Rehabilitation (ABPMR) and Pain Medicine. With over 18 years of clinical experience, Dr. Chang specializes in interventional pain management, neuropathy, arthritis, and spinal conditions, and is fluent in English and Korean.
Services:
- Stem Cell Therapy: ISS offers biologic stem cell injections for orthopedic and musculoskeletal conditions. The clinic positions stem cell therapy as one component of a comprehensive treatment plan, which may also include PRP and physical therapy to maximize outcomes.
- Platelet-Rich Plasma (PRP) Therapy: PRP is drawn from the patient’s own blood, processed on-site, and injected under ultrasound guidance into joints, tendons, or ligament attachment sites to promote tissue healing and reduce inflammation.
- Hyaluronic Acid Injections: Viscosupplementation for joint lubrication, primarily in knee osteoarthritis.
- Interventional Pain Procedures: Epidural steroid injections, nerve blocks, trigger point injections, facet injections, and radiofrequency ablation for spine-related and chronic pain conditions.
- SI Joint Injections and Peripheral Joint Injections: Diagnostic and therapeutic injections for sacroiliac joint dysfunction and extremity joint pain.
Conditions Treated:
- Knee, hip, shoulder, and spine osteoarthritis
- Cartilage damage and joint degeneration
- Rotator cuff tears and shoulder impingement
- ACL, MCL, and meniscus injuries
- Labral tears (hip and shoulder)
- Tendon injuries (Achilles, patellar, elbow)
- Chronic lower back and neck pain
- Sciatica and radiculopathy
- Sacroiliac joint dysfunction
- Plantar fasciitis
- Muscle strains and soft tissue injuries
Technology and Equipment: The Riverside clinic uses ultrasound guidance for injection procedures and operates certified laboratory facilities for on-site processing of biologic preparations.
Insurance and Pricing: Medicare and PPO plans accepted. Self-pay options available. Patients are advised to contact the clinic directly to verify coverage for specific regenerative procedures, as biologic therapies are often not covered by insurance.
2. Omar Kadri, M.D. — Orthopedic Surgery and Regenerative Medicine, Riverside
Address: 4500 Brockton Avenue, Suite 204, Riverside, CA 92501
Phone: (951) 296-6676
Website: https://www.kadriortho.com
Hours: Monday through Friday, 8:00 AM — 6:00 PM
About: Dr. Omar M. Kadri is a board-certified orthopedic surgeon based in Riverside, California, with a primary office at 4500 Brockton Avenue in the 92501 ZIP code and a secondary location in Corona. He is affiliated with Riverside Community Hospital and trained at two of the most recognized institutions in American medicine. His practice focuses on hip and knee conditions, and he offers PRP therapy as a non-surgical intervention for patients who are not yet candidates for joint replacement or who prefer to explore biologic options before surgery. The practice is well suited for patients who want a single provider capable of evaluating the full spectrum of orthopedic care — from regenerative injection to robotic-assisted surgical reconstruction — without being transferred between clinics. Dr. Kadri is registered with Medicare and accepts major commercial insurance plans.
Physicians:
- Omar M. Kadri, MD — Board-Certified Orthopedic Surgeon, Adult Reconstruction and Joint Replacement Fellowship. Dr. Kadri earned his medical degree from the David Geffen School of Medicine at UCLA (2015) and completed his residency in Orthopaedic Surgery at Henry Ford Health in Michigan. He subsequently completed an Adult Reconstruction Fellowship (2020-2021) specializing in hip and knee reconstructive surgery. He is board certified in Orthopedic Surgery, holds California medical license number 170865, and is registered in the National Provider Identifier (NPI) database under NPI 1619362928. He is affiliated with Riverside Community Hospital.
Services:
- PRP (Platelet-Rich Plasma) Injections: Dr. Kadri offers PRP therapy for inflammatory joint conditions, soft tissue injuries, and as a strategy to delay or avoid joint replacement in appropriate candidates. PRP is drawn from the patient’s own blood, concentrated, and injected directly into the affected joint or tissue under clinical guidance.
- Hip and Knee Replacement Surgery: Total and partial hip and knee replacement using Mako SmartRobotics-assisted technology, which enables patient-specific pre-operative planning and intraoperative precision.
- Minimally Invasive Orthopedic Surgery: Dr. Kadri emphasizes minimally invasive surgical approaches to reduce recovery time and post-operative complications.
- Trauma and Fracture Care: Evaluation and surgical management of fractures and acute orthopedic trauma in the hip and knee region.
Conditions Treated:
- Hip and knee osteoarthritis
- Avascular necrosis of the hip
- Joint inflammation and cartilage wear
- Ligament and tendon injuries of the knee
- Hip and knee fractures
- Post-surgical joint pain and hardware complications
Technology and Equipment: The practice uses Mako SmartRobotics technology for joint replacement surgery, enabling individualized surgical planning and real-time intraoperative feedback to improve implant positioning and alignment.
Insurance and Pricing: Medicare accepted. Also accepts Aetna, Humana, Cigna, Blue Cross, United Healthcare, and other major commercial plans. Patients seeking PRP therapy should confirm coverage directly, as biologic injections are frequently excluded from standard orthopedic benefits.
3. R3 Stem Cell — Serving Riverside, CA
Phone: (844) 438-7836 (844-GET-STEM)
Website: https://r3stemcell.com/riverside-ca/
Consultation: Free consultations available by phone or in person
Note on Location: R3 Stem Cell operates as a national network that partners with local physician practices. Their Riverside, CA page serves patients in the area and connects them with affiliated providers. A specific clinic street address and individual physician name for the Riverside location were not publicly listed on their website as of the date of publication. Patients should call (844) 438-7836 or use their location finder at r3stemcell.com to confirm the current affiliated Riverside clinic address and treating physician before scheduling.
About: R3 Stem Cell is one of the larger regenerative medicine networks operating in the United States and internationally, with over 45 affiliated clinic locations across seven countries and more than 26,000 procedures performed. The organization functions as a referral and training network: it partners with independently practicing physicians who have completed R3’s regenerative medicine training program, and markets treatment access to patients through city-specific landing pages. The company reports an 85% patient satisfaction rate across its network. R3’s model is notable in that it bundles consultation and treatment coordination at the network level while the actual clinical care is delivered by locally licensed, independently practicing physicians. This structure means the treating physician at a Riverside R3 affiliate will hold their own independent California medical license and may maintain a primary practice identity separate from the R3 brand.
Services:
- Umbilical Cord and Amniotic Stem Cell Therapy: R3 network clinics offer allogeneic stem cell treatments derived from umbilical cord tissue (Wharton’s Jelly) and amniotic sources, which are processed by licensed tissue banks and injected at the point of care.
- Exosome Therapy: Cell-derived extracellular vesicles used to deliver growth factors and signaling molecules to targeted tissue sites.
- Bone Marrow and Adipose-Derived Stem Cells: Autologous (patient-derived) options for patients who prefer cells harvested from their own body.
- PRP Therapy: Platelet-rich plasma injections for joint, tendon, and soft tissue conditions.
- Peptide and Vitamin Infusion Protocols: Adjunctive regenerative support treatments.
Conditions Treated:
- Back and neck pain
- Shoulder, knee, wrist, and hip joint pain
- Sports injuries and ligament damage
- Arthritis and degenerative joint conditions
- Systemic inflammatory conditions (evaluated case by case)
Regulatory Disclosure: R3 Stem Cell explicitly states on its website that stem cell therapy is considered experimental and is regulated by the FDA, though it is not FDA-approved as a treatment for specific conditions. This transparency is a positive signal in a field where not all providers disclose regulatory status clearly.
What to Know Before Choosing a Stem Cell Clinic in Riverside
Before booking a consultation at any regenerative medicine clinic in Riverside, verify the treating physician’s California medical license at the Medical Board of California website (mbc.ca.gov). This verification takes under two minutes and confirms that the physician is licensed, in good standing, and not subject to disciplinary action. A license number alone is not sufficient — check the actual status. Also ask whether the physician is board certified in a specialty relevant to the condition being treated: a PM&R physician or orthopedic surgeon with formal training in musculoskeletal anatomy is better positioned to deliver accurate diagnostic imaging-guided injections than a provider whose primary specialty is unrelated to the musculoskeletal system.
Ask about imaging guidance before agreeing to any injection procedure. Ultrasound-guided and fluoroscopy-guided injections place the needle at the correct anatomical target with real-time visual confirmation. Blind (landmark-guided) injections are lower cost but carry higher rates of inaccurate needle placement, which reduces efficacy and may increase complication risk. In Riverside, where several reputable PM&R and orthopedic practices offer ultrasound-guided protocols, there is no clinical reason to accept a blind injection for most standard regenerative procedures. Clinics that use imaging guidance demonstrate a higher standard of procedural care.
Clarify the source of the biologic material being used. Autologous treatments (using your own blood for PRP, or your own bone marrow or fat for stem cell procedures) differ significantly from allogeneic treatments (using donor-derived tissue such as umbilical cord-derived Wharton’s Jelly). Neither is inherently superior for all indications, but the distinction matters for informed consent. Ask: where does the material come from, which tissue bank processed it, and what regulatory pathway governs its use? Reputable clinics will answer these questions directly. A clinic that declines to name its tissue supplier or cannot produce an FDA establishment registration for the bank should be regarded with caution.
Finally, ask for realistic outcome expectations with honest data. No biologic therapy should be described as a cure. For conditions such as knee osteoarthritis, the published clinical literature supports modest-to-moderate symptomatic improvement in a subset of patients over six to 24 months — not permanent tissue regeneration in most cases. A physician who presents regenerative medicine as a replacement for evidence-based rehabilitation, activity modification, and appropriate pain management is overstating the current evidence. Conversely, a physician who dismisses regenerative options entirely without reviewing your imaging and history may not be giving you a complete picture of non-surgical options. Riverside has qualified physicians in both PM&R and orthopedic surgery who can give you an honest evaluation — seek a second opinion from a board-certified specialist if a treatment recommendation feels premature or the pricing structure involves packages sold at initial consultation.
Disclaimer: This directory is for informational purposes only. Inclusion does not constitute endorsement of any clinic, physician, or treatment. All clinic details, addresses, phone numbers, and physician credentials reflect information available at the time of research (February 2025) and should be independently verified before scheduling any appointment. Regenerative therapies including stem cell therapy and PRP are not FDA-approved for most musculoskeletal indications and are considered experimental or investigational. Results vary by patient, condition, and provider. Consult a licensed physician and verify credentials with the Medical Board of California at mbc.ca.gov before pursuing any medical treatment.