Overview
Columbus, Ohio has emerged as one of the Midwest’s more active markets for regenerative medicine, driven in part by the presence of The Ohio State University Wexner Medical Center, one of the largest academic medical centers in the United States. OSU’s research infrastructure has cultivated a regional culture of innovation in musculoskeletal and orthopedic care, attracting physicians with advanced training in non-surgical interventions and creating a patient population that is increasingly familiar with the concept of orthobiologic therapies. Independent clinics in the greater Columbus area operate alongside this academic anchor, offering services ranging from platelet-rich plasma (PRP) injections to bone marrow aspirate concentrate (BMAC) therapy and human cellular tissue treatments.
Patients typically seek stem cell therapy in Columbus for one of several reasons: a desire to avoid or delay joint replacement surgery, dissatisfaction with the pain management outcomes of conventional therapies, or an interest in accelerating recovery from soft-tissue injuries such as rotator cuff tears, ligament sprains, or tendinopathies. Many patients arrive after years of cortisone injections, physical therapy, or non-steroidal anti-inflammatory drug use without durable relief. Regenerative approaches are positioned by providers as treatments that address tissue damage at the cellular level rather than simply suppressing symptoms.
Clinic types in Columbus vary considerably. Some practices, such as hospital-affiliated programs at OhioHealth, operate within traditional insurance frameworks and focus specifically on orthopedic indications with imaging-guided injection protocols. Others are independent outpatient clinics that combine regenerative medicine with functional medicine, hormone optimization, and wellness services. A third category consists of multi-location national networks with a local referral or seminar presence. Understanding which category a clinic falls into is important because it affects quality controls, physician oversight, regulatory compliance, and the likelihood that treatments are covered by insurance.
Evaluating a stem cell therapy clinic in Columbus requires attention to a few core factors. The treating provider should hold an active MD or DO license with the State Medical Board of Ohio, and ideally carry relevant board certifications in disciplines such as Physical Medicine and Rehabilitation, Pain Medicine, or Orthopedic Surgery. The source and regulatory status of any biologic material used — whether autologous (derived from the patient’s own body) or allogeneic (from a donor) — matters for both safety and legal compliance under FDA guidelines. Patients should ask specifically whether treatments use FDA-registered tissue products, whether procedures are performed under image guidance (ultrasound or fluoroscopy), and what the clinic’s protocol is for post-procedure follow-up.
Top Stem Cell Therapy Clinics in Columbus
1. Polaris Rejuvenation
Address: 1070 Polaris Pkwy, Suite 110, Columbus, OH 43240
Phone: (614) 427-9296
Website: https://polarisrejuvenation.com
About: Polaris Rejuvenation is an independent outpatient clinic located in the Polaris Parkway corridor of north Columbus, a commercial and medical hub in Franklin County. The practice was founded by Dr. David Garcia, DO, who has been delivering regenerative and anti-aging medicine in the Columbus area since 2006. The clinic operates under a functional medicine model, meaning it attempts to identify and address underlying causes of dysfunction — hormonal, metabolic, and structural — rather than treating symptoms in isolation. In addition to its Columbus location, Polaris Rejuvenation is affiliated with partner wellness centers in Nashville, Fort Lauderdale, and Orange County, California. Dr. Garcia has worked with professional athletes across the NFL, NHL, MLB, and MMA, and is co-author of the book North America’s Top Doctors: Share Secrets to Anti-Aging and Wellness. On Healthgrades, the practice holds an average patient rating of 4.9 out of 5 based on over 111 reviews.
Physicians:
- Dr. David Garcia, DO — Integrative Medicine Specialist, over 35 years of experience. Graduate of Ohio University Heritage College of Osteopathic Medicine (1989). Formerly practiced emergency and urgent care medicine beginning in 1992. Board certified in Anti-Aging Medicine, Stem Cell Therapy, Family Medicine, Occupational Medicine, Emergency Medicine, Independent Medical Examiner, and Addiction Medicine. Fellow in Anti-Aging, Regenerative, and Functional Medicine through the American Academy of Anti-Aging Medicine. Active member of the American Academy of Anti-Aging, Functional, and Regenerative Medicine. Hospital affiliate: OhioHealth Grant Medical Center.
Services:
- Stem Cell Therapy: Regenerative cellular treatments targeting musculoskeletal conditions, tissue repair, and systemic disease management.
- Platelet-Rich Plasma (PRP) and PRF Therapy: Autologous blood-derived concentration injected to promote tissue healing.
- Peptide Therapy: Targeted peptide protocols for recovery, immune function, and systemic health optimization.
- Exosome Therapy: Cell-signaling treatments used to support tissue regeneration.
- NAD IV Therapy: Intravenous nicotinamide adenine dinucleotide infusion for cellular energy and recovery.
- Hormone Therapy (Men and Women): Bioidentical hormone replacement addressing andropause, menopause, thyroid, and adrenal function.
- Weight Management: Semaglutide-based programs.
Conditions Treated:
- Osteoarthritis (knee, hip, shoulder)
- Tendinopathies and ligament injuries
- Back pain and spinal degeneration
- Asthma
- Crohn’s disease
- Fibromyalgia
- Hashimoto’s disease
- Autoimmune disorders
- Kidney and liver disease
- Hormonal imbalances
- Erectile dysfunction and sexual wellness conditions
2. Spine LLC (Dr. Nikesh Batra, MD)
Address: 1090 Beecher Crossing North, Suite A, Gahanna, OH 43230 (Main Office); 6850 Suite D, Perimeter Drive, Dublin, OH 43017 (Satellite Office)
Phone: (614) 392-5336
Website: https://www.columbusspinecare.com
About: Spine LLC is a Columbus-area pain management practice led by Dr. Nikesh Batra, MD, who has practiced interventional pain management in central Ohio since 2002. The practice operates two locations — a main office in Gahanna and a satellite office in Dublin — with Monday through Friday hours from 8:00 AM to 4:00 PM. Spine LLC integrates regenerative medicine into a broader pain management platform that includes fluoroscopy-guided injections, spinal cord stimulation, and electrodiagnostic testing. The practice is registered with the National Provider Identifier database under NPI number 1780987768. Dr. Batra is affiliated with Marion General Hospital, Dublin Methodist Hospital, and Morrow County Hospital. The clinic accepts new patients and processes many private insurance plans, Medicare, and Medicaid. The practice also maintains a patient portal through mycareweb.net/nbatra and active social media presence.
Physicians:
- Dr. Nikesh Batra, MD — Pain Management Specialist. Medical degree from Sawai Man Singh Medical College, Rajasthan University (1992). Anesthesiology residency at Maimonides Medical Center, New York (completed 2001). Fellowship in Pain Management at the University of Texas Health Science Center at San Antonio (completed 2002). Dual board certification through the American Board of Anesthesiology in Anesthesiology and Pain Medicine. Professional memberships: American Society of Anesthesiologists, International Spine Intervention Society, American Society of Interventional Pain Physicians, Ohio State Medical Association. Published contributor to Ramamurthy, Rogers and Alanmanou’s Decision Making in Pain Management, 2nd Edition (2006).
Services:
- Stem Cell Therapy: Bone marrow-derived, adipose-derived, and allograft amniotic stem cell injections for orthopedic conditions. Procedures are outpatient and typically completed in under one hour.
- Platelet-Rich Plasma (PRP): Autologous blood-concentration injections to accelerate soft-tissue healing.
- Interventional Pain Management: Fluoroscopy-guided epidural steroid injections, nerve blocks, and radiofrequency ablation.
- Spinal Cord Stimulation: Implantable neuromodulation devices for chronic pain.
- EMG/NCS Studies: Electrodiagnostic evaluation of nerve and muscle function.
- Disc Decompression Therapy.
- Sacroiliac Joint Injections.
Conditions Treated:
- Knee arthritis and ligament injuries
- Rotator cuff tears
- Tendonitis and tendinopathy
- Back pain and sciatica
- Hip bursitis
- Plantar fasciitis
- Patellar tendon injury
- Achilles tendon injuries
- Tennis elbow
- Carpal tunnel syndrome
- Complex Regional Pain Syndrome (CRPS)
- Headache disorders
Patient Experience: The practice describes stem cell procedures as minimally invasive, with most patients returning to daily activity the next day. Clinical improvement is typically expected within 4 to 6 weeks, with continued progress possible for up to 12 months following treatment.
Insurance and Pricing: The practice accepts many private insurance plans, Medicare, and Medicaid. Regenerative medicine procedures may be subject to out-of-pocket costs depending on the patient’s specific plan; patients are advised to contact the office directly to confirm coverage.
3. ReGen Medical Ohio
Address: 74 S. Liberty Street, Suite B, Powell, OH 43065
Phone: (614) 547-2474
Website: https://regenmedicalohio.com
About: ReGen Medical Ohio is a regenerative medicine clinic located in Powell, a suburb of Columbus in Delaware County, approximately 18 miles north of downtown Columbus. The practice was founded by Dr. Ripal Parikh, DO, who has been delivering regenerative medicine since 2011 and traces his clinical focus to training under his late mentor, Dr. Jeff Ericksen, a recognized Prolotherapy specialist. ReGen Medical operates on a philosophy of identifying and resolving the structural root cause of pain rather than masking symptoms through pharmaceutical suppression. The clinic serves patients from Powell, Dublin, Westerville, Delaware, Worthington, Hilliard, Gahanna, Galena, and Columbus proper. Dr. Parikh is an active member of the Hackett Hemwall Foundation, has lectured at their annual conference on Prolotherapy for shoulder pain, and has participated in two international medical missions treating pain with Prolotherapy. Office hours are Tuesday and Thursday from 9:00 AM to 5:00 PM and Saturday from 9:00 AM to 2:00 PM.
Physicians:
- Dr. Ripal Parikh, DO — Physical Medicine and Rehabilitation specialist. Board certified in Physical Medicine and Rehabilitation and Pain Medicine. Osteopathic Physician with a special interest in Musculoskeletal Medicine and Regenerative Medicine. Trained in regenerative medicine fellowship under Dr. Jeff Ericksen. Active member of the Hackett Hemwall Foundation, an organization dedicated to evidence-based Prolotherapy education and global pain care access. Has personally undergone Prolotherapy treatment for a knee condition, an experience he credits with shaping his clinical approach.
Services:
- Prolotherapy: Dextrose-based injection therapy targeting ligament and tendon laxity to stimulate connective tissue repair. The clinic describes this as a cornerstone treatment distinct from steroid or anesthetic injections.
- Platelet-Rich Plasma (PRP): Autologous platelet concentration injections for acute and chronic soft-tissue injury.
- Trigger Point Injections: Targeted injections into myofascial trigger points for pain relief.
- Functional Medicine Consultations: Detailed laboratory analysis for hormone optimization, metabolic efficiency assessment, and lifestyle intervention planning.
Conditions Treated:
- Knee injuries and degenerative joint disease
- Degenerative disc disease
- Arthritic hands and wrists
- Morton’s neuroma
- Post-herpetic neuralgia
- Hypermobile Ehlers-Danlos Syndrome (hEDS)
- Back and neck pain
- Sciatica-type leg pain
- Headaches
- Fatigue, inflammation, and chronic pain conditions
Patient Experience: Patient accounts consistently describe Dr. Parikh as spending 45 minutes or more in the initial examination and consultation, with detailed explanation of diagnoses and treatment rationale before any procedure begins. Reviewers on third-party platforms have noted him as particularly knowledgeable about complex connective tissue conditions such as hEDS.
What to Know Before Choosing a Stem Cell Clinic in Columbus
The first question to ask any Columbus-area regenerative medicine clinic is whether the biologic material used in your treatment comes from your own body (autologous) or from a third-party tissue bank (allogeneic). Autologous treatments — in which stem cells are harvested from your own bone marrow or adipose (fat) tissue during the same appointment — require no FDA biologics license application for the tissue itself, since the material never leaves your body. Allogeneic products, including amniotic membrane allografts, umbilical cord tissue, and other donor-derived biologics, are subject to FDA oversight and must come from registered tissue establishments. Patients should ask clinics to confirm the regulatory status of any donor-derived products and whether the tissue supplier holds current FDA registration. Marketing claims that describe donor products as containing “live stem cells” are frequently disputed by the FDA and independent researchers; patients should apply skepticism to these claims and request the clinic’s specific product documentation.
Imaging guidance during injection is a meaningful quality indicator. Ultrasound-guided or fluoroscopy-guided delivery of regenerative biologics into a target joint or soft-tissue structure substantially increases the likelihood that the material reaches the intended anatomical location. Freehand injections — performed without real-time imaging — carry a higher risk of extra-articular placement and reduced efficacy. In Columbus, larger pain management practices with fluoroscopy suites, such as Spine LLC, typically offer imaging-guided procedures as standard. Patients at any clinic should ask specifically whether image guidance will be used and which modality.
Laboratory processing matters when autologous biologics are involved. If a clinic uses PRP, ask whether they process it in a closed, FDA-cleared system or an open centrifuge system, and what the target platelet concentration is. For bone marrow aspirate concentrate (BMAC), ask whether the clinic performs the aspiration in-house under imaging guidance and what the processing protocol is. For adipose-derived cell therapies, ask about the enzymatic versus mechanical processing distinction, as FDA guidance treats these differently. These are not obscure questions — any physician running an autologous regenerative medicine program should be able to answer them without hesitation.
Verifying physician credentials before committing to treatment is straightforward in Ohio. The State Medical Board of Ohio maintains a public license lookup at med.ohio.gov where any physician’s active license status, board certifications, and disciplinary history can be confirmed by name. For additional verification, the American Board of Medical Specialties (ABMS) and the American Osteopathic Association (AOA) maintain searchable certification databases. In Columbus specifically, the density of academic medical institutions means that independent verification of credentials is easy, and patients should take advantage of it. A physician who holds board certification in Physical Medicine and Rehabilitation, Pain Medicine, or Sports Medicine, and who has completed a fellowship in a relevant discipline, provides a more defensible clinical foundation for regenerative medicine practice than one whose primary training is outside musculoskeletal medicine.
Disclaimer: This directory is for informational purposes only. Inclusion does not constitute endorsement. Verify credentials and consult a licensed physician before pursuing any treatment.