Overview
Houston sits at the center of one of the most concentrated medical ecosystems in the world. The Texas Medical Center, anchored in the Museum District and spanning more than 1,000 acres, is the largest medical complex on earth, housing over 60 institutions, 21 hospitals, and dozens of research facilities. This infrastructure shapes what is available to patients in the broader Houston metropolitan area: physician-led, specialty-focused clinics that sit outside the academic hospital system but draw on the research culture and clinical standards that the TMC establishes as a baseline. For patients seeking stem cell and regenerative medicine therapies, Houston represents one of the few American cities where genuine depth of specialist expertise is accessible outside of major university hospitals.
Patients come to Houston-area stem cell clinics for a narrow but significant set of reasons. Most are managing musculoskeletal conditions, orthopedic degeneration, or chronic pain that has not responded adequately to conventional treatment, physical therapy, or surgery. Conditions such as osteoarthritis of the knee and hip, degenerative disc disease, rotator cuff tears, and tendon injuries are the most commonly addressed. A smaller subset seeks regenerative treatments for neuropathy, sports injuries, or autoimmune-related tissue damage. What they share is a preference for minimally invasive intervention and a desire to stimulate the body’s own repair mechanisms rather than rely solely on pharmaceutical management or elective surgery.
The Houston-area market for regenerative medicine includes several distinct clinic types. Physical medicine and rehabilitation specialists bring imaging-guided injection expertise combined with a rehabilitation framework. Interventional pain management physicians approach the same anatomy from an anesthesiology and pain-block background, offering a different procedural skill set. Orthopedic surgeons who have incorporated regenerative techniques provide continuity from conservative to surgical care. Each type has a different risk-benefit calculus and a different procedural vocabulary. Patients benefit from understanding these distinctions before committing to a treatment course.
Evaluating any stem cell clinic requires scrutiny of several factors that are not always prominently displayed. The sourcing and processing of biological material matters: autologous treatments (drawn from the patient’s own bone marrow or adipose tissue) carry a different regulatory and scientific profile than allogeneic products derived from donor tissue. Imaging guidance during injection is a direct indicator of procedural precision. Physician credentials, particularly board certification in the relevant specialty and fellowship training, separate independently practicing specialists from general practitioners who have added regenerative services to a broader menu. The clinics below have been selected based on verifiable physical addresses, physician-led structures with MD credentials, and active websites with publicly documented service information.
Top Stem Cell Therapy Clinics in Houston
1. Stem Cell Center Houston — James D. Weiss, M.D., P.L.L.C.
Address: 5373 W. Alabama St., Suite 204, Houston, TX 77056
Phone: (713) 583-1848
Website: https://www.stemcellcenterhouston.com
About: The practice of James D. Weiss, M.D. operates from the Galleria corridor of Houston, one of the city’s most accessible medical office districts, and has built its clinical identity around nonsurgical spine and joint care with regenerative medicine as its primary intervention. Dr. Weiss brings more than 30 years of interventional spine experience to each patient encounter, a tenure that spans the evolution of regenerative medicine from early experimental protocols to current practice standards. The clinic positions itself as a destination for patients who have exhausted or wish to avoid surgical routes for conditions involving the spine, joints, and soft tissue, emphasizing minimal complication risk and procedures that stimulate the body’s own tissue regrowth capacity. Training affiliations listed by the practice include Baylor College of Medicine, Mount Sinai, Maimonides Medical Center, Rosalind Franklin University of Medicine and Science, and NYU Langone Medical Center, reflecting a career grounded in major academic medical institutions before independent practice. The clinic has earned a 4.6-star rating across 130 patient reviews, and additional locations serve Austin and Pearland, Texas.
Physicians:
- Dr. James D. Weiss, M.D. — Physical Medicine and Rehabilitation; Fellow of the American Academy of Physical Medicine and Rehabilitation; specialty areas include age management, functional medicine, regenerative medicine, sports medicine, spine care, and interventional pain; training affiliations with Baylor College of Medicine, Mount Sinai, NYU Langone, and Rosalind Franklin University of Medicine and Science; more than 30 years in interventional spine and regenerative medicine practice
Services:
- Regenerative Cell Therapy: Autologous stem cells are extracted from the patient’s own bone marrow under imaging guidance. The procedure typically takes less than one hour with same-day discharge, and the concentrated cells are injected precisely into the target site using fluoroscopic (X-ray) guidance to maximize placement accuracy.
- Platelet Rich Plasma (PRP) Therapy: Blood is drawn from the patient, processed to concentrate growth factors and platelets, and injected into the injured area. PRP is used to accelerate healing in soft tissue and joint conditions, and is frequently combined with other regenerative approaches.
- Bone Marrow Aspiration Concentrate (BMAC): Bone marrow is aspirated from the patient’s pelvis, concentrated in a processing unit to isolate stem cells and growth factors, and injected into the target joint or spinal structure under imaging guidance.
- Autologous Adult Cell Therapy: Treatment using the patient’s own harvested cells, minimizing immunological risk and aligned with FDA regulatory frameworks for autologous procedures.
- Electromyography (EMG): Diagnostic nerve conduction and muscle function testing used to characterize the degree and location of neurological involvement in pain and degenerative conditions.
- Life Care Plans and Independent Medical Reviews: Forensic and case management services for patients with complex, long-term care needs.
Conditions Treated:
- Degenerative disc disease
- Collapsed disc
- Herniated disc
- Failed back surgery syndrome
- Back pain (acute and chronic)
- Neck pain
- Joint pain
- Arthritis
- Sports injuries
- Soft tissue injuries (muscle, ligament, tendon)
- Bone-related injuries
- Chronic pain
Technology and Equipment:
Procedures are performed under fluoroscopic (special X-ray) guidance to ensure precise delivery of stem cells and injectates to the target anatomical site. Bone marrow concentrate procedures use specialized processing equipment to isolate and concentrate cellular components. EMG/nerve conduction studies are conducted in-office for diagnostic purposes.
Patient Experience:
Appointments are available through online booking and direct phone inquiry. The practice provides patient education resources including video content and documented case testimonials. The typical stem cell procedure is performed as an outpatient, takes under one hour, and patients are discharged the same day. Dr. Weiss conducts an individualized evaluation before determining candidacy for any regenerative procedure.
2. Texas Pain and Regenerative Medicine
Address: 11226 Southwest Freeway, Suite A, Houston, TX 77031
Phone: (832) 536-9891
Website: https://www.texaspainrm.com
About: Texas Pain and Regenerative Medicine is a physician-led pain management practice on the southwest side of Houston, serving patients from the Sugar Land, Missouri City, and broader southwest Harris County corridor. The practice is built around the clinical philosophy of multi-modal treatment: rather than defaulting to a single intervention, Dr. Fahed combines interventional pain procedures, regenerative medicine, and individualized therapeutic approaches based on detailed diagnostic evaluation of each patient’s condition. The clinic accepts patients seeking alternatives to long-term opioid therapy, surgical intervention, or patients for whom prior conventional treatments have provided incomplete relief. Dr. Fahed’s background in anesthesiology and interventional pain management gives him procedural expertise in precisely targeted injections guided by diagnostic imaging, a skill set that directly supports the accuracy of stem cell and PRP delivery. The practice is a member of the American Society of Interventional Pain Physicians, situating it within a national framework of evidence and procedural standards for this specialty. Office hours run Monday through Friday, 8:30 AM to 5:00 PM, and appointment scheduling is available by phone.
Physicians:
- Dr. Samir Fahed, M.D. — Board certified by the American Board of Anesthesiology and in Interventional Pain Management; specialty in pain management and alternative medicine; graduated from the University of Damascus Faculty of Medicine; completed anesthesiology residency at the University of Toledo Medical Center, Ohio; member of the American Medical Association and the American Society of Interventional Pain Physicians
Services:
- Stem Cell Therapy: Biologic cells are selected and injected into areas of damaged tissue, with the goal of stimulating the body’s natural repair process. Dr. Fahed conducts detailed diagnostic testing before determining whether stem cell therapy is appropriate for a given patient, and tailors the treatment protocol to the specific injury or degenerative condition.
- Platelet-Rich Plasma (PRP): Blood is drawn from the patient and processed to concentrate platelets and growth factors, which are then injected into the site of injury. PRP can be used as a standalone treatment or in combination with stem cell protocols for additive effect.
- Interventional Pain Management: A range of minimally invasive procedures targeting specific pain generators, including spinal injections, nerve blocks, and joint procedures, tailored to the individual patient’s diagnostic profile.
- Alternative Medicine Treatments: Non-pharmacological and non-surgical approaches integrated into comprehensive pain management plans.
Conditions Treated:
- Back pain
- Neck pain
- Sciatica
- Fibromyalgia
- Neuropathy
- Chronic pain
- Spinal cord compression
- Facet joint syndrome
- Degenerative disc disease
- Herniated disc
- Headaches (migraine, tension, cluster)
- Complex regional pain syndrome (CRPS)
- Tendon injuries (tendonitis, partial tears)
- Sports injuries: ACL tears, meniscus tears, rotator cuff tears
- Arthritis
- Fractures
Technology and Equipment:
Minimally invasive injection procedures are used to deliver stem cells and PRP with precision. Diagnostic testing is conducted prior to regenerative procedures to confirm appropriate candidacy and target the correct anatomical structures.
Patient Experience:
The practice follows a research-driven intake process: patients undergo a detailed examination and diagnostic evaluation before any regenerative treatment is recommended. Following stem cell or PRP procedures, patients can typically expect initial swelling to resolve within two to three weeks, with measurable improvement appearing in as little as four to six weeks. Personalized treatment packages may combine regenerative medicine with other therapeutic modalities. The practice runs Monday through Friday, and appointments can be scheduled at (832) 536-9891.
3. Seifert M.D. — Dr. Heidi J. Seifert, Interventional Pain Management
Address: 3100 Timmons Lane, Suite 120, Houston, TX 77027
Phone: (713) 655-7246
Website: https://www.heidiseifertmd.com
About: Seifert M.D. is an interventional pain management practice located in the River Oaks and Greenway Plaza corridor of Houston, serving patients from Bellaire, Sugar Land, Friendswood, and the broader Houston metropolitan area. Dr. Heidi Seifert is a dual board-certified physician in anesthesiology and pain medicine whose clinical focus is the diagnosis and treatment of acute and chronic musculoskeletal and spinal pain using minimally invasive, evidence-based techniques. The practice has developed a particularly comprehensive regenerative medicine program offering several distinct biologics-based interventions, including BMAC stem cell therapy, Lipogems fat-derived cell therapy, PRP with platelet-derived growth factor enhancement, prolotherapy, and laser-based tissue stimulation. Dr. Seifert takes a multidisciplinary approach, coordinating care with physical therapists, acupuncturists, and chiropractors to ensure patients have access to a full continuum of regenerative treatment. The practice uses advanced diagnostic imaging to identify pain sources precisely before custom-tailoring the regenerative protocol, and has earned a 4.5-star patient rating across 23 reviews. The website is described as offering treatments in Houston for spine, joints, and musculoskeletal conditions across the full body.
Physicians:
- Dr. Heidi J. Seifert, M.D. — Interventional pain management specialist; board certified by the American Board of Anesthesiology and the American Board of Pain Medicine; specializes in diagnostic and therapeutic spinal injections and state-of-the-art regenerative techniques for pain and tissue regeneration across the spine, joints, and musculoskeletal system; practice serves Houston, Bellaire, Sugar Land, and Friendswood
Services:
- BMAC (Bone Marrow Aspirate Concentrate) Stem Cell Therapy: Bone marrow is aspirated from the patient’s pelvic bone under local anesthetic using a small needle, then processed in a specialized high-tech unit that concentrates the stem cells, platelets, and growth factors. The resulting concentrate is collected in a sterile syringe and injected into the specific area of injury. Stem cells within the concentrate have the capacity to transform into different tissue types, supporting the rebuilding of damaged muscle, tendon, ligament, and cartilage.
- Lipogems (Fat-Derived Cell Therapy): An FDA-cleared, minimally invasive procedure performed in approximately one hour under local anesthesia. Adipose (fat) tissue is harvested from the patient’s abdomen through a small incision, then processed using state-of-the-art Lipogems technology to harvest, concentrate, and transfer the patient’s own cells to the injured area. Lipogems provides both regenerative cellular activity and a cushioning effect for damaged tissue.
- PRP and PDGF (Platelet-Derived Growth Factor) Injections: A next-generation PRP protocol that concentrates platelet-derived growth factors from the patient’s own blood and injects them into the site of injured or inflamed tissue. This approach provides pain relief, reduces inflammation, and triggers natural tissue growth. PDGF enhancement adds additional growth factor specificity compared to standard PRP.
- Prolotherapy: Injection-based treatment that introduces a proliferant solution into weakened or injured ligament and tendon attachments, triggering a localized inflammatory response that stimulates collagen production and tissue strengthening. Indicated for unresolved pain in ligament and tendon injuries where standard conservative care has been insufficient.
- Phoenix Thera-Lase Laser Therapy: A non-invasive bio-stimulation laser system that delivers concentrated, continuous-wave light energy to deeper tissue layers for enhanced therapeutic benefit. Used to treat both acute and chronic pain, stimulating cellular repair and reducing inflammation without injection.
Conditions Treated:
- Osteoarthritis of the shoulder, knee, hip
- Rotator cuff tears and AC joint injuries
- Recurrent shoulder dislocation
- Shoulder cartilage and tendon injuries
- Knee pain and cartilage degeneration
- Wrist and hand pain
- Elbow pain and lateral epicondylitis
- Head and neck pain
- Low back pain
- Herniated disc
- Degenerative disc disease
- Disc tear
- Spondylolisthesis
- Spinal stenosis
- Radiculopathy (pinched nerve)
- Osteoporosis-related compression fractures
- Nerve cysts
- Shingles-related pain
- Ligament and tendon injuries across multiple body regions
Technology and Equipment:
The practice uses advanced diagnostic imaging to identify and precisely localize pain sources prior to any regenerative intervention. BMAC procedures use a specialized high-tech processing unit for stem cell concentration. Lipogems procedures use the FDA-cleared Lipogems device for adipose tissue processing and transfer. The Phoenix Thera-Lase system provides non-invasive laser therapy as a standalone or adjunctive treatment. Dr. Seifert also employs the most advanced diagnostic systems available to custom-tailor each patient’s regenerative treatment plan.
Patient Experience:
Each patient undergoes an individualized evaluation in which Dr. Seifert uses advanced diagnostic tools to identify the specific source of pain and determine the most appropriate regenerative intervention. The practice takes a multidisciplinary and holistic approach, actively coordinating with physical therapists, acupuncturists, and chiropractors as part of the patient’s broader care team. Follow-up protocols are built into the treatment plan to monitor tissue response and adjust care accordingly. The clinic serves patients from across Houston and surrounding communities including Bellaire, Sugar Land, and Friendswood.
What to Know Before Choosing a Stem Cell Clinic in Houston
The first question to ask any regenerative medicine clinic in Houston is where the biological material comes from and how it is processed. Autologous treatments — those using the patient’s own bone marrow or fat tissue — carry a distinct regulatory and clinical profile compared to allogeneic products sourced from donor tissue or umbilical cord. The FDA regulates how these materials are classified, and autologous same-day procedures fall under a different framework than minimally manipulated allogeneic products. Ask the clinic explicitly: is this my own tissue or a donor product, and what processing steps are applied before injection. In-house processing performed on the same day using a validated, cleared device is the standard that reputable autologous stem cell clinics maintain.
Imaging guidance during injection is not optional in a credible regenerative medicine practice. Injection accuracy determines whether the cellular material reaches the target tissue or is deposited in surrounding structures. Ultrasound guidance allows real-time visualization of needle position relative to soft tissue anatomy. Fluoroscopic (X-ray) guidance is the standard for spinal injections and deeper joint structures. Ask every clinic directly: what imaging do you use to guide the injection, and will the physician perform the procedure or will it be delegated to a mid-level provider. If a clinic cannot confirm image-guided delivery or cannot specify which imaging modality is used, that is a meaningful clinical differentiator that should inform your decision.
Board certification verification is straightforward and free. The American Board of Medical Specialties maintains a public search tool at abms.org where any patient can confirm whether a physician is board certified, in which specialty, and whether certification is current. In Houston’s competitive market, physician credentials are not always front-facing. Look for board certification in a specialty directly relevant to the procedure being offered: Physical Medicine and Rehabilitation for musculoskeletal and spine work, Anesthesiology or Pain Medicine for interventional injection procedures, or Orthopedic Surgery for joint-related structural repair. Fellowship training in interventional pain, sports medicine, or regenerative medicine adds further relevant expertise.
Pricing transparency is a useful proxy for institutional maturity. Stem cell therapies are rarely covered by insurance in their current form, and clinics that are straightforward about pricing, package structures, and what is included in each consultation tend to operate with more consistency and fewer surprises. Ask for a written treatment plan before committing to any procedure. A reputable Houston clinic will provide a documented protocol specifying the biological source, processing method, delivery approach, imaging used, and follow-up schedule. If the answer is a verbal assurance with no documentation, that is a signal worth weighing. Patient outcomes in regenerative medicine are variable and the evidence base is still developing — a clinic that is honest about this, rather than promotional, is operating from the right foundation.
Disclaimer: This directory is for informational purposes only. Inclusion does not constitute endorsement. Verify credentials and consult a licensed physician before pursuing any treatment.