Nashville has emerged as one of the South’s most significant healthcare hubs, anchored by world-class institutions including Vanderbilt University Medical Center, TriStar Health, and Ascension Saint Thomas. This concentration of medical infrastructure has created a fertile ground for specialty and regenerative medicine practices to flourish across Davidson County and the surrounding communities of Brentwood, Franklin, and Lebanon. Patients in the Nashville metropolitan area have access to a range of regenerative medicine providers, from large academic centers conducting clinical trials to independent specialty practices offering outpatient orthopedic and musculoskeletal treatments.
Patients seek stem cell therapy and related regenerative treatments for a wide variety of reasons, most commonly chronic joint pain, orthopedic injuries, arthritis, and the desire to delay or avoid surgical intervention. Regenerative medicine procedures — which include platelet-rich plasma (PRP) injections, prolotherapy, bone marrow aspirate concentrate (BMAC), and the use of structural tissue products — are designed to harness the body’s own healing mechanisms. Rather than masking symptoms, the goal is to encourage tissue repair at the injury site. For patients who have had limited success with conventional treatments such as corticosteroid injections, physical therapy alone, or pain management protocols, these therapies represent an increasingly discussed alternative pathway.
Clinics in the Nashville area fall into broadly distinct categories. Some are hospital-affiliated or academically connected practices where fellowship-trained orthopedic surgeons incorporate orthobiologics into a broader surgical and non-surgical practice. Others are integrative medicine facilities that take a whole-patient view, combining regenerative injection therapy with functional medicine, nutrition, and lifestyle optimization. A third category consists of specialized outpatient stem cell centers that focus primarily or exclusively on autologous (patient-derived) cell treatments for orthopedic conditions. Understanding which type of clinic aligns with your specific condition and treatment goals is the first step in making an informed decision.
Evaluating a stem cell clinic in Nashville requires scrutiny of several key factors. The treating physician’s credentials are paramount: look for board certification through the American Board of Orthopaedic Surgery, the American Board of Physical Medicine and Rehabilitation, or another relevant specialty board. Fellowship training in sports medicine, musculoskeletal medicine, or orthobiologics adds further evidence of specialized expertise. Verify that the clinic uses image guidance (ultrasound or fluoroscopy) during injections, as precision in needle placement is directly tied to treatment outcomes. Ask specifically whether the therapy involves your own cells (autologous) or donor-derived products, as each carries distinct regulatory and safety considerations. Finally, confirm that the facility operates in compliance with applicable FDA guidelines, which as of 2026 classify most orthopedic stem cell treatments as investigational.
Top Stem Cell Therapy Clinics in Nashville
1. Paul D. Crook, MD — Orthopaedic Surgery and Regenerative Medicine
Address: 8 City Blvd, Suite 300, Nashville, TN 37209 (ONEC1TY Campus, West Nashville) Phone: (615) 823-8891 Website: paulcrookmd.com
About: Dr. Paul D. Crook operates an orthopedic surgery practice at Nashville’s ONEC1TY medical campus, a modern mixed-use development on the city’s west side that has attracted a cluster of specialty healthcare providers. His practice encompasses the full spectrum of orthopedic care for the shoulder, hip, and knee, with regenerative medicine offerings integrated as a non-surgical treatment option for appropriate candidates. Dr. Crook’s approach positions stem cell therapy and PRP not as standalone alternatives to medical care but as tools within a comprehensive orthopedic treatment strategy. Patients are evaluated for eligibility based on the nature and extent of their injury or degenerative condition before any regenerative protocol is recommended. The practice maintains affiliations with TriStar Centennial Medical Center and Ascension Saint Thomas Hospital, providing continuity of care for patients who may eventually require surgical intervention. Dr. Crook also maintains a second office location in Dickson, TN, extending his practice’s reach across the broader Middle Tennessee region.
Physicians:
- Dr. Paul D. Crook, MD — Board-certified orthopedic surgeon with fellowship training in sports medicine. Completed his medical degree at the University of Tennessee Health Science Center College of Medicine. Specializes in shoulder, hip, and knee conditions. Has served as team physician for Montgomery Bell Academy, Texas A&M football, the Houston Sabercats rugby team, and the San Antonio Missions Triple-A baseball team. Rated 4.8/5 across 71 verified patient reviews.
Services:
- Platelet-Rich Plasma (PRP) Injection: A concentration of the patient’s own platelets is prepared from a blood draw and injected into the target area. PRP delivers growth factors that support tissue healing and are used for a range of orthopedic injuries and degenerative joint conditions.
- Stem Cell Therapy / Orthobiologics: Stem cells are used to renew and repair damaged or diseased tissues. Dr. Crook applies these therapies to orthopedic conditions of the shoulder, hip, and knee, typically as part of a broader non-surgical management plan.
- Bone Grafting and Structural Repair: For patients who require surgical intervention, orthobiologic materials can be incorporated to support healing and tissue regeneration.
Conditions Treated:
- Shoulder injuries (rotator cuff tears, labral injuries, glenohumeral arthritis)
- Hip conditions (labral tears, hip arthritis)
- Knee injuries and osteoarthritis
- Sports-related musculoskeletal injuries
- Tendon and ligament injuries
Technology and Equipment: Image-guided injection procedures. Hospital-affiliated surgical facilities at TriStar Centennial and Ascension Saint Thomas for cases requiring operative management.
Patient Experience: Patients consistently report that Dr. Crook takes time to explain diagnosis and treatment options thoroughly before recommending a course of action, and that both surgical and non-surgical pathways are presented with equal consideration.
2. MaxWell Clinic — Regenerative Injection Therapy (Dr. Scott Stoll, MD)
Address: 103 Continental Place, Suite 300, Brentwood, TN 37027 Phone: (615) 370-0091 Website: maxwellclinic.com
About: MaxWell Clinic was founded in 2003 by Dr. David Haase and has grown into a 12,000-square-foot integrative functional medicine facility in Brentwood, a city directly south of Nashville along I-65 and part of the contiguous Nashville metropolitan area. The clinic’s core philosophy is whole-patient care: rather than treating symptoms in isolation, the clinical team looks at root causes, lifestyle factors, and systemic health as part of every treatment plan. The regenerative medicine program at MaxWell is led by Dr. Scott Stoll, who brings over 20 years of experience in regenerative injection therapy to the practice. Dr. Stoll’s approach integrates physical assessment, advanced imaging, and a personalized treatment protocol that addresses not just the injection site but also nutrition, sleep, stress, and movement patterns as components of the healing process. The clinic draws patients from across Middle Tennessee as well as out-of-town patients who travel specifically for Dr. Stoll’s expertise. MaxWell Clinic operates Monday through Friday from 8:00 AM to 5:00 PM.
Physicians:
- Dr. Scott Stoll, MD, FABPMR — Board-certified physician in Physical Medicine and Rehabilitation (American Board of Physical and Rehabilitation Medicine). Medical degree from the University of Colorado. Certified in ultrasound-guided injections and fluoroscopy. Over 20 years of experience in regenerative injection therapy. Former member of the 1994 U.S. Olympic Bobsled team and current physician for the U.S. Bobsled and Skeleton teams. Co-founder of the Plantrician Project and the International Plant Based Nutrition Healthcare Conference. Recognized internationally as a leader in regenerative musculoskeletal medicine and lifestyle medicine.
- Dr. David Haase, MD, IFMCP, QIA — Founder of MaxWell Clinic. Double board-certified in Family Medicine and Integrative Holistic Medicine. Graduate of Vanderbilt University School of Medicine with residency completed at the Mayo Clinic in Rochester, MN. Lead Faculty for the Institute for Functional Medicine.
Services:
- Prolotherapy: Injection of a solution containing dextrose into damaged ligaments and tendons to stimulate the body’s natural repair process. Dr. Stoll uses prolotherapy as a first-line regenerative option for ligament laxity, chronic tendon pain, and certain spine conditions.
- Platelet-Rich Plasma (PRP) Therapy: Concentrated platelets derived from the patient’s own blood, rich in growth factors and cytokines, are injected under imaging guidance into the injured tissue. Particularly effective for osteoarthritis, chronic tendinopathies, and soft tissue injuries.
- Structural Tissue Products: Ethically sourced biological materials containing growth factors, cytokines, and signaling molecules that recruit the body’s own stem cells to promote regeneration of cartilage, tendons, and muscle. Used when PRP alone may not be sufficient for the degree of tissue damage present.
- Comprehensive Regenerative Consultation: Each new patient receives a full physical assessment, review of medical history, and personalized treatment planning that encompasses imaging, injection therapy, and adjunctive lifestyle guidance.
Conditions Treated:
- Osteoarthritis (knee, hip, shoulder, spine)
- Chronic tendinopathy (Achilles, patellar, rotator cuff, elbow)
- Ligament injuries and laxity
- Spine and low back conditions
- Musculoskeletal injuries in athletes and active adults
- Degenerative joint disease
Technology and Equipment: Ultrasound-guided and fluoroscopy-guided injections. Advanced imaging for pre-treatment assessment. The clinic operates as a 12,000-square-foot integrative facility with diagnostic and therapeutic capabilities on-site.
Patient Experience: MaxWell Clinic is known for longer appointment times than typical specialty practices, reflecting the integrative model’s emphasis on thorough evaluation and patient education. Out-of-town patients can coordinate multi-day visit schedules that consolidate consultations, testing, and treatment.
3. Vita Nova Stem Cell Professionals (Dr. Hemal V. Mehta, MD)
Address: 4601 Carothers Parkway, Suite 325, Franklin, TN 37067 Phone: (615) 801-8005 Website: vitanovatn.com
About: Vita Nova Stem Cell Professionals is a Franklin-based regenerative medicine practice serving patients throughout the greater Nashville metropolitan area. The clinic’s defining characteristic is a commitment to full-cycle quality control: stem cells are harvested from the patient’s own body, processed in an on-site laboratory under direct physician supervision, and delivered under ultrasound or fluoroscopic guidance with documented cell count and viability reports provided to every patient prior to treatment. This level of transparency — knowing exactly what is being administered and in what concentration — is uncommon in the regenerative medicine field and reflects the practice’s stated mission of honest, evidence-guided care. Vita Nova does not operate on a one-size-fits-all model; each patient receives an individualized care plan based on their specific condition, health goals, and treatment history. The practice explicitly states that if regenerative therapy is not appropriate for a given patient’s situation, that assessment will be communicated directly rather than proceeding regardless of candidacy.
Physicians:
- Dr. Hemal V. Mehta, MD — Board-certified in Physical Medicine and Rehabilitation and board-certified in Pain Medicine. Specializes in non-opioid therapy for joint pain, osteoarthritis, spine pain, and neuropathy. Recognized as a leading authority in Regenerative Medicine with a clinical focus on reducing pain and improving function through evidence-guided protocols.
Services:
- Autologous Stem Cell Therapy: Cells are harvested from the patient’s own body, expanded in the on-site laboratory with full quality oversight, and injected into the target site under image guidance. Each patient receives documentation of cell count and viability prior to the day of procedure.
- Platelet-Rich Plasma (PRP) Therapy: Concentrated platelet preparations drawn from the patient’s blood and injected to support tissue repair and reduce inflammation in joints, tendons, and soft tissue structures.
- A2M (Alpha-2-Macroglobulin) Therapy: A protein-based joint protection therapy targeting cartilage degradation and inflammatory pathways, used primarily for osteoarthritis and joint pain.
- IV Therapy and Red Light Therapy: Adjunctive wellness protocols including direct-infusion nutrient therapy and medical-grade photobiomodulation for systemic support and recovery optimization.
Conditions Treated:
- Orthopedic: neck pain, back pain, knee pain, joint degeneration
- Neurological: multiple sclerosis, autism spectrum support
- Systemic and organ-related: autoimmune diseases, heart disease, lung disease, kidney disease
- Wellness and anti-aging: cellular rejuvenation, immune support
Technology and Equipment: In-house autologous cell processing laboratory with documented viability reporting. Ultrasound-guided and fluoroscopic injection delivery. Full in-office procedure capability with direct physician oversight from cell collection through administration.
Patient Experience: Vita Nova emphasizes that patients receive individualized attention throughout the care process — from consultation through follow-up. The practice’s transparency protocol, which includes providing written cell count and viability documentation before treatment proceeds, is cited as a key differentiator by patients comparing regenerative medicine providers in the Nashville area.
Insurance and Pricing: Regenerative therapies at Vita Nova are generally not covered by insurance given their investigational classification for most indications. Contact the practice directly at (615) 801-8005 or info@vitanovatn.com to discuss current pricing, care plan options, and consultation scheduling. Office hours are Monday through Friday, 8:00 AM to 5:00 PM.
What to Know Before Choosing a Stem Cell Clinic in Nashville
Before scheduling a consultation at any regenerative medicine practice in Nashville or the surrounding area, prepare a specific list of questions that will help you evaluate whether the clinic and physician are appropriate for your condition. Ask directly: What type of stem cell product will be used, and is it derived from my own body or from a donor source? How many procedures of this type has the treating physician performed, and what does the practice’s own outcome data show? Will imaging guidance be used during the procedure, and can you see documentation of that protocol? What follow-up care is included in the treatment fee, and what happens if the initial treatment does not produce the expected result? Clinics that cannot answer these questions clearly, or that make outcome guarantees, should be approached with caution. Legitimate regenerative medicine practices are transparent about the investigational status of many of these therapies and do not promise specific results.
Diagnostic imaging is an important part of any pre-treatment workup. Before your consultation, gather any existing MRI, X-ray, or CT imaging related to the affected area. Most Nashville-area regenerative medicine physicians will want to review prior imaging to understand the degree of joint degeneration, cartilage loss, or soft tissue damage before recommending a treatment approach. In some cases, musculoskeletal ultrasound will be performed on-site during the consultation itself, as this allows real-time dynamic assessment of tendons, ligaments, and joint spaces. Patients who arrive with comprehensive imaging records allow the consulting physician to spend more time on treatment planning rather than on gap-filling diagnostic workup.
Verifying physician credentials independently is a step that every prospective patient should take regardless of how polished a clinic’s website appears. The Tennessee Department of Health maintains a publicly accessible license verification portal where you can confirm that any physician holding a Tennessee medical license is in good standing and has no disciplinary history. For orthopedic surgeons, the American Board of Orthopaedic Surgery (ABOS) offers a public certification lookup. For physical medicine and rehabilitation specialists, the American Board of Physical Medicine and Rehabilitation (ABPMR) provides similar verification. Fellowship training can often be confirmed through the physician’s profile on hospital-affiliated directories, NPI Registry entries, or the practice website. Board certification is not a guarantee of treatment quality, but it is a minimum credentialing standard that every patient should verify before proceeding.
Nashville’s healthcare market also includes providers who advertise stem cell therapy with limited physician oversight or who use marketing language that overstates the evidence base for certain treatments. The FDA has issued warnings to clinics that administer unapproved stem cell products, including some that use adipose-derived stromal cells or umbilical cord-derived products in ways that fall outside current regulatory guidance. When evaluating any Nashville-area clinic, ask specifically whether their protocols have been reviewed for FDA compliance and whether the physician can explain the regulatory classification of the product they intend to use. Patients who take the time to ask these questions, verify credentials, and consult with a primary care physician or orthopedic specialist before committing to a regenerative treatment are better positioned to make a decision that aligns with both the evidence and their individual health circumstances.
Disclaimer: This directory is for informational purposes only and was compiled from publicly available sources as of February 2026. Inclusion of any clinic or physician does not constitute endorsement, recommendation, or validation of treatment efficacy. Clinic information including addresses, phone numbers, and physician affiliations may change; verify all details directly with the provider before scheduling. Stem cell and regenerative medicine therapies are in many cases investigational and not approved by the FDA for specific orthopedic indications. Consult a licensed and board-certified physician before pursuing any medical treatment.