Overview
Scottsdale, Arizona has established itself as one of the country’s most concentrated corridors for advanced medical care and wellness-focused medicine. The greater Phoenix-Scottsdale metro hosts dozens of specialty clinics, surgical centers, and integrative practices, making it a destination not only for Arizona residents but for patients traveling from across the Southwest and beyond. The city’s infrastructure — from HonorHealth’s network of hospitals to an unusually dense population of fellowship-trained specialists — creates an environment where patients can access subspecialty regenerative medicine without traveling to Los Angeles, Dallas, or New York. That density also means patients have real choices, and real choices require real evaluation criteria.
Regenerative medicine, including stem cell therapy and platelet-rich plasma (PRP), draws patients who are navigating a specific kind of crossroads: they have a musculoskeletal diagnosis — osteoarthritis, a tendon injury, a labral tear, chronic joint degeneration — and they are either not surgical candidates, are seeking to delay surgery, or want to exhaust non-surgical options before committing to an operating room. Scottsdale’s orthopedic and sports medicine community has responded to this demand with practices that range from single-physician boutique clinics to multi-provider centers offering full imaging and laboratory workup alongside biological treatments. Patients seeking care here will encounter a field that is both scientifically serious and commercially noisy; separating the two requires knowing what to look for.
The term “stem cell therapy” covers a range of approaches. Autologous therapies use the patient’s own biological material — bone marrow aspirate concentrate (BMAC), adipose-derived stromal vascular fraction (SVF), or platelet-rich plasma drawn from peripheral blood. These are the approaches practiced by licensed physicians under their state medical license and are the standard of care in this space. Allogeneic or “off-the-shelf” amniotic or umbilical products occupy a more contested regulatory space, and patients should ask any clinic explicitly what the source of the cells or growth factors is, whether the product is FDA-registered, and whether the procedure is being performed by the treating physician or delegated to non-physician staff. In Scottsdale, you will find both ends of that spectrum, which makes physician credential verification a prerequisite rather than an afterthought.
When evaluating any clinic in this directory — or any clinic in the country — the most important filter is physician qualification. Board certification by the American Board of Orthopaedic Surgery, the American Osteopathic Board of Anesthesiology, or a comparable specialty board signals that the physician completed an accredited residency and passed rigorous written and oral examinations. Fellowship training in pain medicine, sports medicine, or orthopedic surgery adds a layer of subspecialty depth. Fellowship programs at institutions like Stanford, the Steadman Clinic, or the Hughston Clinic are nationally recognized and carry significant clinical weight. A physician who lists credentials but does not specify the certifying board, the fellowship institution, or the year of training may be obscuring gaps. This guide presents three Scottsdale-area clinics with verifiable addresses, physician credentials confirmed through public licensing and professional databases, and active HTTPS websites as of the research date.
Top Stem Cell Therapy Clinics in Scottsdale
1. Precision Regenerative Medicine
Address: 8591 E Bell Rd, Suite 104, Scottsdale, AZ 85260
Phone: (602) 806-7389
Website: https://precisionmedprp.com
About: Precision Regenerative Medicine is a specialty clinic built around a single clinical focus: orthobiologic cell therapy for musculoskeletal conditions. The practice uses only autologous biological material — the patient’s own blood, bone marrow, or adipose tissue — which means no off-the-shelf or donor-derived products are administered. The clinic’s approach emphasizes diagnostic precision before any injection is placed, with ultrasound and fluoroscopy guidance used to confirm accurate delivery to the target structure. This image-guided approach distinguishes the practice from clinics that rely on anatomical landmark injection, which carries a higher risk of inaccurate placement. The clinic operates Monday through Friday and is positioned in north Scottsdale, accessible from the Bell Road corridor.
Physicians:
- Dr. Tammy Penhollow, DO — Dr. Penhollow holds a Doctor of Osteopathic Medicine from Kirksville College of Osteopathic Medicine. She completed a fellowship in Pain Medicine at Stanford University School of Medicine (2011-2012) and is double board certified in Anesthesiology and Pain Medicine by the American Society of Anesthesiologists. Prior to her Scottsdale practice, she served as a physician in the United States Navy, including deployment to Kosovo in support of Operation Joint Guardian, and served as Head of the Department of Anesthesia at US Naval Hospital Rota, Spain. She holds academic appointments as Assistant Professor of Anesthesiology at Uniformed Services University of the Health Sciences and Instructor of Anesthesiology at Mayo Clinic College of Medicine and Science.
Services:
- Platelet-Rich Plasma (PRP) Therapy: Concentrated growth factors drawn from the patient’s own blood are injected into damaged soft tissue or joints to stimulate repair cascades in tendons, ligaments, cartilage, and muscle.
- Bone Marrow Aspirate Concentrate (BMAC): Bone marrow is harvested from the posterior iliac crest, concentrated via centrifuge, and injected into the target structure. BMAC contains mesenchymal stromal cells and a broad cytokine profile suited for degenerative joint conditions.
- Adipose-Derived Cell Therapy: A small volume of fat tissue is harvested via mini-lipoaspirate, processed to isolate the stromal vascular fraction, and redeployed to the treatment site.
- Prolotherapy: Concentrated dextrose injections used to stimulate connective tissue regeneration in ligamentous laxity or chronic tendon pathology.
- EMSculpt NEO: High-intensity focused electromagnetic therapy used as a rehabilitation adjunct following regenerative procedures to accelerate muscle reactivation.
- Knee Boost System and Shoulder Boost System: Proprietary multi-modal treatment protocols combining orthobiologics with targeted rehabilitation sequencing.
Conditions Treated:
- Knee osteoarthritis and chondral defects
- Shoulder rotator cuff tendinopathy and partial tears
- Spine disc degeneration, facet arthropathy, and surrounding ligament/muscle pathology
- Hip labral degeneration and iliofemoral ligament laxity
- Plantar fasciitis and Achilles tendinopathy
- Elbow and wrist tendinopathy (including lateral epicondylitis)
- Acute and chronic soft tissue injuries in athletes and active adults
Technology and Equipment: Ultrasound-guided and fluoroscopy-guided injection delivery; EMSculpt NEO (HIFEM technology) for neuromuscular rehabilitation adjunct.
Patient Experience: Dr. Penhollow conducts consultations and performs procedures directly, without delegation to non-physician providers. The clinic’s north Scottsdale location on the Bell Road corridor offers easy access from Scottsdale, Paradise Valley, and north Phoenix.
2. Athletic Institute of Medicine
Address: 9475 East Ironwood Square Drive, Suite 100, Scottsdale, AZ 85258
Phone: (480) 778-1400
Website: https://athleticinstituteofmedicine.com
About: The Athletic Institute of Medicine is an orthopedic and sports medicine practice founded and led by Dr. Thomas J. Wall, who brings a rare combination of clinical and research credentials to regenerative medicine. The practice addresses the full spectrum of orthopedic conditions, with a regenerative medicine track designed for patients who want to postpone or avoid surgical intervention. Dr. Wall’s philosophy is that the body’s own biology, when properly concentrated and precisely delivered, can interrupt degenerative cycles in joints and soft tissue that would otherwise progress to surgical necessity. The Scottsdale location serves patients from across the East Valley and is complemented by a Mesa satellite office. The practice operates within the HonorHealth network, with Dr. Wall affiliated with HonorHealth Scottsdale Thompson Peak Medical Center.
Physicians:
- Dr. Thomas J. Wall, MD, PhD — Dr. Wall holds both an MD and a PhD in Neuromuscular Physiology, the study of the biomechanical and neurological mechanisms governing how the body moves and recovers. He graduated from Temple University Lewis Katz School of Medicine in 1990 and completed his orthopedic surgical residency at Penn State Hershey Medical Center. His post-graduate fellowship training was completed at two of the country’s most respected orthopedic institutions: the Hughston Clinic in Columbus, GA, and the Steadman Clinic in Vail, CO, where he trained under Marc J. Philippon, internationally recognized for hip arthroscopy. Dr. Wall is board certified in both Orthopedic Surgery and Sports Medicine and is a Fellow of the American Academy of Orthopaedic Surgery. He has been named Phoenix Top Doc in Sports Medicine by peer nomination on multiple occasions and previously held a clinical professorship at Southwest College of Naturopathic Medicine.
Services:
- Stem Cell Therapy (Autologous): Bone marrow aspirate concentrate and adipose-derived stem cells harvested from the patient and re-introduced to target joints or soft tissue. Dr. Wall also has experience with allogeneic biologics; patients should discuss source and regulatory status directly during consultation.
- Platelet-Rich Plasma (PRP): Ultrasound-guided PRP injection for tendons, ligaments, cartilage surfaces, and joint capsule structures.
- Alpha-2 Macroglobulin (A2M) Therapy: A2M is a plasma protein that functions as a broad-spectrum protease inhibitor, theorized to counteract cartilage breakdown in early-to-moderate osteoarthritis.
- Telehealth Consultations: Initial evaluation and follow-up available via telehealth for patients outside immediate driving range.
- Surgical Referral Coordination: For patients whose pathology exceeds non-surgical thresholds, Dr. Wall maintains a network of subspecialty surgeons and can facilitate rapid referral.
Conditions Treated:
- Knee osteoarthritis, ACL pathology, meniscal degeneration, and chondral defects
- Shoulder rotator cuff tears, labral pathology, frozen shoulder, and glenohumeral instability
- Hip degeneration, labral tears, and femoroacetabular impingement (non-surgical candidates)
- Elbow, wrist, and ankle tendon/ligament injuries
- Cartilage restoration in athletic and aging populations
- Muscle tears, strains, and chronic tendinopathy
Technology and Equipment: Ultrasound-guided injection procedures; VERILAST and VISIONAIRE knee systems for patients who transition to surgical care; centrifuge processing for PRP and bone marrow concentrate.
Patient Experience: Dr. Wall is accepting new patients and offers telehealth appointments. The practice accepts multiple insurance plans, though regenerative procedures are typically classified as out-of-pocket; patients should verify specific coverage during scheduling. The Scottsdale office is located in the Ironwood Square complex near the Shea/101 corridor.
3. Center for Regenerative Cell Medicine
Address: 7425 E Shea Blvd, Suite 107, Scottsdale, AZ 85260
Phone: (480) 998-7999
Website: https://www.mystemcelltherapy.com
About: The Center for Regenerative Cell Medicine occupies a distinct position in the Scottsdale market as a practice with documented early-adoption history in adipose-derived stem cell therapy. Dr. Todd Malan has been working with fat-derived stromal vascular fraction since 2009 and has contributed to the medical literature through chapters in two regenerative medicine textbooks, as well as presentations at international stem cell conferences. The clinic divides its clinical focus between cosmetic applications of regenerative biology and regenerative medicine research for patients with chronic disease and degenerative disorders. This dual focus means the practice sees a patient population that ranges from aesthetic enhancement to serious systemic and musculoskeletal conditions. The clinic is affiliated with HonorHealth Scottsdale Shea Medical Center and operates Monday through Friday. The Shea Boulevard location places it centrally within the north Scottsdale medical corridor.
Physicians:
- Dr. Todd K. Malan, MD — Dr. Malan received his undergraduate degree from Brigham Young University and his MD from the University of Arizona College of Medicine, graduating in the top 10 percent of his class in May 1993. He completed his residency training at Walter Reed Army Medical Center and Bethesda Naval Hospital in Washington, DC, and is board certified in Obstetrics and Gynecology. He is an associate of the American Academy of Cosmetic Surgeons, a founding member of the American Academy of Cosmetic Physicians, a member of the California Academy of Cosmetic Surgery, and a member of the American Academy of Anti-Aging Medicine. In October 2009, Dr. Malan was the first US physician documented to use adipose-derived stem cells for soft tissue reconstruction. He has subsequently trained hundreds of physicians internationally in safe protocols for stem cell harvesting and deployment. His entry into regenerative medicine was motivated in part by a close family member’s diagnosis of multiple sclerosis.
Services:
- Adipose-Derived Stromal Vascular Fraction (SVF) Therapy: A mini-lipoaspirate procedure harvests a small volume of the patient’s own fat tissue, which is then processed to isolate mesenchymal stromal cells, pericytes, and growth factors contained in the SVF. The concentrate is redeployed to target tissues.
- Cosmetic Regenerative Procedures: Fat transfer and stem cell-enhanced cosmetic procedures including facial rejuvenation and body contouring using autologous biological material.
- Regenerative Medicine Research Applications: The clinic maintains a research-oriented track for patients with conditions including COPD, multiple sclerosis, and other chronic or degenerative disorders. Patients considering this track should request a detailed consultation to understand the investigational nature of these applications.
- Peyronie’s Disease and Erectile Dysfunction Treatment: Regenerative approaches applied to urological conditions, an area where Dr. Malan’s OB/GYN and cosmetic background intersects with his regenerative medicine expertise.
- Lichen Sclerosus Treatment: Regenerative approaches for this chronic dermatological condition.
Conditions Treated:
- Soft tissue volume loss and cosmetic deformity (reconstructive and aesthetic)
- Chronic degenerative conditions (research track; patients should request full disclosure of evidence basis)
- Urological conditions including Peyronie’s disease and erectile dysfunction
- Lichen sclerosus
- Musculoskeletal degeneration (consult required to determine eligibility)
Technology and Equipment: Proprietary adipose processing protocols developed by Dr. Malan; mini-lipoaspirate harvest technique; centrifuge-based SVF isolation.
Patient Experience: The clinic’s Shea Boulevard location places it within a dense cluster of Scottsdale medical offices. Hours are Monday through Friday, 8:30 AM to 4:30 PM.
What to Know Before Choosing a Stem Cell Clinic in Scottsdale
The most important question any patient can ask a Scottsdale stem cell clinic is: who performs the procedure, and what are their specific credentials in injection-based medicine? In many clinics, a physician conducts the initial consultation but the injection is administered by a nurse practitioner, physician assistant, or other mid-level provider. For superficial PRP injections into easily accessible tendons, this may carry acceptable risk. For intra-articular injections near neurovascular structures — spine, hip, shoulder — the technical precision required is significantly higher, and fellowship training in interventional pain medicine, orthopedic surgery, or musculoskeletal radiology becomes clinically relevant. Ask directly: will the board-certified physician perform the injection under imaging guidance, or will it be delegated? The clinics in this directory are identified as physician-led, but the question should be posed and answered in writing before any procedure is scheduled.
Second, any clinic offering regenerative therapy should be able to walk you through a clear diagnostic pathway before injecting anything. That pathway should include, at minimum, a review of prior imaging (MRI is the standard for soft tissue and cartilage pathology) or an order for imaging if none exists, a physical examination specific to the target structure, and a documented rationale for the biological agent selected. A clinic that offers PRP, BMAC, and SVF without differentiation — as if all three are interchangeable for all conditions — is not practicing precision medicine. PRP is the most evidence-supported option for many tendon and early joint conditions. BMAC carries a different risk profile and evidence base. SVF involves a harvest procedure with its own surgical considerations. You should understand which product is being proposed, why it was selected for your specific diagnosis, and what the peer-reviewed evidence base looks like for that application in your condition.
Third, Scottsdale patients should verify physician credentials independently through the Arizona Medical Board (azmd.gov) before scheduling any procedure. The Medical Board maintains a public database of licensed physicians, including board certification status, any disciplinary history, and current license standing. For DO physicians, the Arizona Board of Osteopathic Examiners in Medicine and Surgery (azome.gov) maintains a parallel database. Cross-checking a physician’s claimed credentials against the Arizona Medical Board record and the relevant specialty board’s verification tool (abos.org for orthopedic surgery, asahq.org for anesthesiology) takes approximately five minutes and eliminates the most common form of credential inflation in this market. No reputable clinic will object to a patient conducting this verification.
Fourth, understand the regulatory landscape that applies to any product being proposed. The FDA distinguishes between procedures that use the patient’s own minimally manipulated biological material (which are generally permitted under the physician’s practice of medicine) and products that require an Investigational New Drug (IND) application or Biologics License Application (BLA). Autologous PRP and same-day bone marrow concentrate generally fall within the minimally manipulated category. More extensively processed cell products, allogeneic amniotic or umbilical products, or any procedure described as a “clinical trial” or “research protocol” should prompt you to ask for the FDA registration number, the IRB approval documentation if applicable, and a clear explanation of your rights as a research subject versus a paying patient. Scottsdale has reputable clinics operating within the appropriate regulatory framework; it also has clinics that do not. Asking these questions before any financial commitment is made is the most reliable way to determine which category you are dealing with.
Disclaimer: This directory is for informational purposes only and reflects publicly available information as of February 2026. Inclusion does not constitute endorsement of any clinic, physician, or treatment. Physician credentials, addresses, phone numbers, and services are subject to change; verify all information directly with the clinic before scheduling. Stem cell therapy and regenerative medicine procedures are not universally FDA-approved and may be considered experimental for many conditions. Consult a licensed physician and review relevant peer-reviewed evidence before pursuing any treatment. Credential verification through the Arizona Medical Board (azmd.gov) is strongly recommended for all providers.